PEA3 TRANSCRIPTION FACTORS AND WNT1-INDUCED MOUSE MAMMARY NEOPLASIA.

The role of the PEA3 subfamily of Ets transcription factors in breast neoplasia is controversial.Although overexpression of PEA3 (E1AF/ETV4), and of the related factors ERM (ETV5) and ER81 (ETV1), have been observed in human and mouse breast tumors, PEA3 factors have also been ascribed a tumor suppressor function.Here, we utilized the MMTV/Wnt1 mou

A major hurdle for blood-based proteomic diagnostics is efficient transport of specimens from the collection site to the testing laboratory.Dried blood spots have shown utility for diagnostic applications, specifically those where red blood cell hemolysis and contamination of specimens with hemoglobin is not confounding.Conversely, applications tha